Chemoinformatics: Directions Toward Combating Neglected Diseases

An Overview of Tropical Parasitic Diseases: Causative Agents, Targets and Drugs

Author(s): Carlton Anthony Taft and Carlos Henrique Tomich de Paula da Silva

Pp: 174-196 (23)

DOI: 10.2174/978160805183011201010174

* (Excluding Mailing and Handling)


There is a need for improved treatments for diseases including protozoan parasitic diseases, such as chagas, malaria, trypanosomiasis, leishmaniasis, onchocerciasis, schistosomiasis, filariasis, toxoplasmosis, cryptosporidiosis, filardiasis and giardiasis. The existing chemotherapy for these diseases is not sufficiently effective due to factors such as toxicity, drug resistance and different strain sensitivities. New chemotherapies are needed to help in the control and prevention of these parasitic diseases.

Keywords: Tropical diseases, causative agents, drug targets.

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