Nanopharmacology and Nanotoxicology: Clinical Implications and Methods

Advances in Dentistry Nanopharmacology

Author(s): Simin Sharifi, Mahdieh Alipour, Atefeh Abedi, Yalda Rahbar Saadat and Solmaz Maleki Dizaj *

Pp: 168-194 (27)

DOI: 10.2174/9789815079692123010010

* (Excluding Mailing and Handling)


Nanotechnology has been widely used in medicine to improve the therapeutic results of various diseases. Much effort has been focused on developing new nanoparticles and determining the physicochemical properties of nanoparticles in relation to their biological fate and performance. Today, nanotechnology has been able to offer effective treatments for use in dentistry. However, in the design and evaluation of these nanotechnology-based drug delivery systems in dentistry, less attention has been paid to the pharmacology of delivered drugs and their pathophysiology. In this chapter, we discuss some recent advances in nanotechnology for drug delivery in dentistry for demineralization, osseointegration of dental implants, the treatment of oral cancer, pain management of dental pulp, and the anti-inflammatory and antimicrobial formulations as well as the role of nanopharmacology in preventive dentistry.

Keywords: Dentistry, Drug delivery, Dental materials.

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