Nanopharmacology and Nanotoxicology: Clinical Implications and Methods

Nanomedicine in Nephrology and Urinary Tract Infection

Author(s): Sepideh Zununi Vahed, Mohammadreza Ardalan and Yalda Rahbar Saadat *

Pp: 82-99 (18)

DOI: 10.2174/9789815079692123010007

* (Excluding Mailing and Handling)


Nanomedicine is an evolving trend in the biomedical field that can be used for the diagnosis, molecular targeting, imaging, and therapy of a wide range of diseases. The kidneys are essential organs that regulate blood pressure, filtrate blood and remove metabolic waste, produce hormones, and balance electrolytes. The kidney has gained great attention in nanomedicine due to its roles in the clearance of the nanodrugs and affecting the pharmacokinetics of these drugs. Nanoparticles can be used for the diagnosis and treatment of kidney diseases including acute kidney injury (AKI), chronic kidney disease (CKD), and glomerular diseases. Different approved nanodurgs have been developed for the treatment of kidney diseases. In this chapter, we summarize the available nanodrugs for the treatment of kidney diseases and urinary tract infections.

Keywords: Rarefied flow, Nanoparticle, Nanomedicine, Drug delivery, Nephrology, Kidney.

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