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Recent Advances in Drug Delivery and Formulation

Editor-in-Chief

ISSN (Print): 2667-3878
ISSN (Online): 2667-3886

Review Article

Formulation Consideration of Medicated Chewing Gum: A Review

Author(s): Kishan Bobe, Yoesh Suryawanshi, Virendra Gomase, Muizz Kachhi and Chandrashekhar Bobade*

Volume 18, Issue 2, 2024

Published on: 17 April, 2024

Page: [100 - 109] Pages: 10

DOI: 10.2174/0126673878281000240411073412

Price: $65

Abstract

In recent times, technological and scientific advances have been made in studying and developing orally delivered medication. Such studies demonstrate the importance of the oral route among patients. The accuracy of drug delivery is very important to achieve a successful therapeutic effect in the case of various pharmaceutical products. A novel drug delivery system adds new benefits or advantages to a drug. This review covers all the aspects of medicated chewing gum (MCG) as a new drug delivery method, including the benefits and drawbacks, manufacturing methods, type of MCG, composition of chewing gum, evaluation parameters, factors that affected the release of API, its pharmaceutical significance, various marketed chewing gum and chewing gum packaging. Chewing gum as a drug delivery system has the potential to cure or prevent various indications, such as analgesic, CNS stimulation, smoking cessation, motion sickness, and treatment and prevention of dental caries or gingivitis. Pharmaceutical distribution to the oral mucosa can be made more convenient and enticing with the help of MCG. Compared to conventional techniques, this delivery system has a longer-lasting effect, which makes it a viable option for treating digestive problems, headaches, migraines, coughing, anxiety, and allergies.

Keywords: Pharmaceutical significance, oral route, MCG, oral drug delivery, smoking cessation, motion sickness.

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