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Current Nanomedicine


ISSN (Print): 2468-1873
ISSN (Online): 2468-1881

Review Article

Nanostructured Lipid Carrier for Dermatological Application: A Comprehensive Review and Future Perspective

Author(s): Bhawana Singh, Manish Kumar, Prabhat Kumar Upadhyay* and Amit Kumar Singh

Volume 14, Issue 3, 2024

Published on: 04 October, 2023

Page: [188 - 199] Pages: 12

DOI: 10.2174/0124681873274871230927105142

Price: $65


Dermatological disease states have psychological impacts that affect a patient’s life. In the management of such disorders, topical delivery has an important role. However, the conven-tional topical delivery systems suffer from various limitations, like skin irritation, a minute quan-tity of drugs reaching disease sites, and over and under medication, which leads to an adverse re-action and therapeutic failure, respectively. Therefore, researchers continuously search for an al-ternate delivery system for treating skin disease. In recent years, nanostructured lipid carriers (NLC) have emanated as promising carrier systems for topical delivery. The current review pro-vides an in-depth insight into topical administration for treating a variety of dermatological issues using NLCs as a carrier. This review highlights the suitability of NLCs as carriers for topical de-livery, their method of preparation, and their characterization. In the present review, the main emphasis has been given to the management of various dermatological problems by using NLCs as a carrier; a plethora of literature investigating NLC as the carrier for topical delivery has been included in this review. In this paper, an attempt has been made to provide a summary of the re-search carried out in this field that will encourage further research in this arena.

Keywords: NLC, topical delivery, dermatological problem, skin, atopic dermatitis, cosmetic agent.

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